Side effects of Ozempic injection In general, the mild side effects of Ozempic are manageable or temporary as long as you take the medicine.But when you stop taking Ozempic, it may take about five weeks after your last dose for the medicine to pass out of your body. Therefore, you may experience adverse effects during this time. Let me share with you my experience with Ozempic side effects. Side effects in the first month When you take the first dose of 0.25 mg of Ozempic, you will experience nausea, constipation, loss of appetite, and indigestion. After the second dose of 0.25 mg, the side effects will start in full force and you will experience constipation, sulfur gas, bloating, and loss of appetite. Some people also experience diarrhea, so taking the dose of Ozempic on an empty stomach is better. Second month In the second month, at a dose of 0.50 mg, nausea and vomiting last only two to three days after taking it, but you will still have a loss of appetite, fatigue, constipation, and gas. Third month: In the third month, when taking 1mg dose, you will lose more weight and see weakness and fatigue; for some people, even